- #SIDE EFFECTS OF PARALLEL ON MAC UPDATE#
- #SIDE EFFECTS OF PARALLEL ON MAC MANUAL#
- #SIDE EFFECTS OF PARALLEL ON MAC FULL#
- #SIDE EFFECTS OF PARALLEL ON MAC SOFTWARE#
Given this context, a number of questions suggest themselves: (1) does every CPU produce the same results (2) is there any interaction between the processes running simultaneously on the same workstation (3) does every workstation produce the same results?
#SIDE EFFECTS OF PARALLEL ON MAC FULL#
Since FreeSurfer is CPU-intensive (20–30 hours per brain for a full segmentation is not exceptional), it is common practice to distribute the computational load among the available central processor units (CPUs) on a single workstation and/or among several workstations. Finally, it has been shown that Freesurfer is capable of reliably capturing (subtle) morphological and pathological changes in the brain (e.g.,, ). In addition, the scan-rescan variability of a number of subcortical brain volumes was assessed –.
Some of these studies addressed the effect of scanner-specific parameters, including field strength, pulse sequence, scanner upgrade, and vendor (cortical thickness:, volume: ).
Also the reliability of the measurements was subject of a number of investigations.
#SIDE EFFECTS OF PARALLEL ON MAC MANUAL#
The measurement of cortical thickness was validated against histological analysis and manual measurements. A number of reported studies discussed the accuracy of the technique by comparing the volume of specific brain structures, such as the hippocampus or amygdala, with manually derived volumes –. Martinos Center for Biomedical Imaging, Harvard-MIT, Boston) comprises a popular and freely available set of tools for deriving neuroanatomical volume and cortical thickness measurements from automated brain segmentation ( ), recently summarised by Fischl. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist.įreeSurfer (Athinoula A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.įunding: This work was supported by the Geestkracht program of the Dutch Health Research Council (ZON-MW, grant number 1), and the European Community's Seventh Framework Program under grant agreement No. Received: JanuAccepted: Published: June 1, 2012Ĭopyright: © 2012 Gronenschild et al. PLoS ONE 7(6):Įditor: Satoru Hayasaka, Wake Forest School of Medicine, United States of America
(2012) The Effects of FreeSurfer Version, Workstation Type, and Macintosh Operating System Version on Anatomical Volume and Cortical Thickness Measurements. Moreover, in view of the large and significant cross-version differences, it is concluded that formal assessment of the accuracy of FreeSurfer is desirable.Ĭitation: Gronenschild EHBM, Habets P, Jacobs HIL, Mengelers R, Rozendaal N, van Os J, et al.
#SIDE EFFECTS OF PARALLEL ON MAC UPDATE#
The main conclusion is that in the context of an ongoing study, users are discouraged to update to a new major release of either FreeSurfer or operating system or to switch to a different type of workstation without repeating the analysis results thus give a quantitative support to successive recommendations stated by FreeSurfer developers over the years. The observed differences are similar in magnitude as effect sizes reported in accuracy evaluations and neurodegenerative studies. About a factor two smaller differences were detected between Macintosh and Hewlett-Packard workstations and between OSX 10.5 and OSX 10.6. Significant differences were revealed between FreeSurfer version v5.0.0 and the two earlier versions. Using a set of 30 anatomical T1-weighted 3T MRI scans, we investigated the effects of data processing variables such as FreeSurfer version (v4.3.1, v4.5.0, and v5.0.0), workstation (Macintosh and Hewlett-Packard), and Macintosh operating system version (OSX 10.5 and OSX 10.6). However, little if any is known about measurement reliability across various data processing conditions.
#SIDE EFFECTS OF PARALLEL ON MAC SOFTWARE#
FreeSurfer is a popular software package to measure cortical thickness and volume of neuroanatomical structures.
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